Amr Nouraldeen
Lexicon Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Carcinogens and Genotoxicity Assessment, Computational Drug Discovery Methods, Drug Solubulity and Delivery Systems, Diabetes Treatment and Management, Sulfur Compounds in Biology
Most-Cited Works
- → Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime (LX2931) and (1R,2S,3R)-1-(2-(Isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932)(2010)110 cited
- → Novel l-Xylose Derivatives as Selective Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitors for the Treatment of Type 2 Diabetes(2009)76 cited
- → Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders(2009)74 cited
- → Modulation of Peripheral Serotonin Levels by Novel Tryptophan Hydroxylase Inhibitors for the Potential Treatment of Functional Gastrointestinal Disorders(2008)72 cited
- → Effect of LX4211 on Glucose Homeostasis and Body Composition in Preclinical Models(2014)51 cited
- → Genetic Deletion of Mst1 Alters T Cell Function and Protects against Autoimmunity(2014)47 cited
- → Molecular interaction of [2,3‐14C] acrylonitrile with DNA in gastric tissue of rat(1994)46 cited
- → Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88(2015)29 cited
- → Chloroacetonitrile (CAN) induces glutathione depletion and 8-hydroxylation of guanine bases in rat gastric mucosa(1999)27 cited
- → Pulmonary toxicity of acrylonitrile: covalent interaction and effect on replicative and unscheduled DNA synthesis in the lung(1992)24 cited