Tatsuya Tamaoki
Kyowa Kirin (Japan)(JP)
Publications by Year
Research Areas
Microbial Natural Products and Biosynthesis, Bioactive Compounds and Antitumor Agents, Cancer therapeutics and mechanisms, Marine Sponges and Natural Products, Synthesis and Biological Activity
Most-Cited Works
- → Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase(1986)2,458 cited
- → Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C(1989)1,115 cited
- → Inhibition of protein kinase C by calphostin C is light-dependent(1991)369 cited
- → [28] Use and specificity of staurosporine, UCN-O1, and calphostin C as protein kinase inhibitors(1991)335 cited
- → Staurosporine inhibits tyrosine-specific protein kinase activity of Rous sarcoma virus transforming protein p60.(1987)263 cited
- → Potent and Specific Inhibitors of Protein Kinase C of Microbial Origin(1990)261 cited
- → Hypericin and pseudohypericin specifically inhibit protein kinase C: Possible relation to their antiretroviral activity(1989)222 cited
- Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models.(1991)
- → UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities.(1989)156 cited
- → Calphostins (UCN-1028), novel and specific inhibitors of protein kinase C. I. Fermentation, isolation, physico-chemical properties and biological activities.(1989)148 cited