Lawrence C. Kuo
Janssen (United States)(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, HIV Research and Treatment, Amino Acid Enzymes and Metabolism, Protein Structure and Dynamics, Hepatitis C virus research
Most-Cited Works
- → Pulsed Doppler echocardiographic determination of stroke volume and cardiac output: clinical validation of two new methods using the apical window.(1984)735 cited
- → Determination of parameters of left ventricular diastolic filling with pulsed Doppler echocardiography: comparison with cineangiography.(1985)533 cited
- → Inhibition of Hepatitis C Virus RNA Replication by 2′-Modified Nucleoside Analogs(2003)337 cited
- → Determination of regurgitant fraction in isolated mitral or aortic regurgitation by pulsed Doppler two-dimensional echocardiography(1986)258 cited
- → Quantification of atrial contribution to left ventricular filling by pulsed Doppler echocardiography and the effect of age in normal and diseased hearts(1987)241 cited
- → Inhibition of a Mitotic Motor Protein: Where, How, and Conformational Consequences(2003)203 cited
- → Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation(2017)171 cited
- → Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases(1994)169 cited
- → Kinesin Spindle Protein (KSP) Inhibitors. 9. Discovery of (2S)-4-(2,5-Difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the Treatment of Taxane-Refractory Cancer(2008)156 cited
- → Mutational Anatomy of an HIV-1 Protease Variant Conferring Cross-resistance to Protease Inhibitors in Clinical Trials(1996)154 cited