Karl Miranda
Publications by Year
Research Areas
Phosphodiesterase function and regulation, Signaling Pathways in Disease, Retinal Diseases and Treatments, Angiogenesis and VEGF in Cancer, Histone Deacetylase Inhibitors Research
Most-Cited Works
- → A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase(2009)58 cited
- → Identification of Orally Available Naphthyridine Protein Kinase D Inhibitors(2010)53 cited
- → Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors(2013)46 cited
- → Synthesis and Biological Evaluation of 6-(Alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one Base and Nucleoside Derivatives(2005)46 cited
- → Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D(2010)41 cited
- → The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration(2018)37 cited
- → Discovery of Oral VEGFR-2 Inhibitors with Prolonged Ocular Retention That Are Efficacious in Models of Wet Age-Related Macular Degeneration(2015)29 cited
- → Synthesis and Antiviral Evaluation of 6-(Alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one Nucleosides and Analogues with Ethynyl, Ethenyl, and Ethyl Spacers at C6 of the Furopyrimidine Core(2007)29 cited
- → Synthesis and Biological Evaluation of 3,3-Difluoropyridine-2,4(1H,3H)-dione and 3-Deaza-3-fluorouracil Base and Nucleoside Derivatives(2009)9 cited
- → Synthesis of 3-Deazauridine Analogues with Potential Antitumor Activity(2003)