Sachie Arai
International University of Health and Welfare(JP)
Publications by Year
Research Areas
Neuropeptides and Animal Physiology, Receptor Mechanisms and Signaling, HIV/AIDS drug development and treatment, Pharmacological Receptor Mechanisms and Effects, Pain Mechanisms and Treatments
Most-Cited Works
- → Discovery of the First Potent and Selective Small Molecule Opioid Receptor-like (ORL1) Antagonist: 1-[(3R,4R)-1-Cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl- 1,3-dihydro-2H-benzimidazol-2-one (J-113397)(1999)204 cited
- Requirement of eel Anguilla japonica for essential fatty acids.(1980)
- Oryzacystatins as the first well-defined cystatins of plant origin and their target proteinases in rice seeds.(1991)
- → Synthesis of J-113397, the first potent and selective ORL1 antagonist(2001)37 cited
- → A New Class of Highly Potent Farnesyl Diphosphate-Competitive Inhibitors of Farnesyltransferase(1998)26 cited
- → Stereoselective synthesis of J-104,118 and J-104,123, novel, potent inhibitors of squalene synthase(1996)14 cited
- → Efficient and practical asymmetric synthesis of 1-tert-butyl 3-methyl (3R,4R)-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1,3-dicarboxylate, a useful intermediate for the synthesis of nociceptin antagonists(2009)8 cited
- → A Novel and Efficient Synthesis of 9-(c-4,t-5-Bishydroxymethylcyclopent-2-en-r-1-yl)-9H-adenine (BCA) Having Anti-HIV Activity from Norbornadiene(1992)4 cited
- An anatomical study on the bronchi and pulmonary blood vessels.(1958)
- → A case report: Characteristic plain radiographic findings of a displaced abomasum in a heifer(2021)1 cited