James F. Tobin
Janssen (United States)(US)
Publications by Year
Research Areas
Adipose Tissue and Metabolism, Peroxisome Proliferator-Activated Receptors, Hormonal Regulation and Hypertension, Protein Tyrosine Phosphatases, Lipid metabolism and biosynthesis
Most-Cited Works
- → Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child(2004)1,373 cited
- → A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep(2006)1,243 cited
- → Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses(2001)478 cited
- → Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis(2006)240 cited
- → Stable expression of the bacterial neor gene in Leishmania enriettii(1990)162 cited
- → Structure-Based Optimization of Protein Tyrosine Phosphatase 1B Inhibitors: From the Active Site to the Second Phosphotyrosine Binding Site(2007)157 cited
- → Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12(2000)154 cited
- → Targeting Acyl-CoA:Diacylglycerol Acyltransferase 1 (DGAT1) with Small Molecule Inhibitors for the Treatment of Metabolic Diseases(2011)151 cited
- → Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent(2008)148 cited
- → Normal Food Intake and Body Weight in Mice Lacking the G Protein-Coupled Receptor GPR39(2006)148 cited