Karen Rex
Amgen (United States)(US)Université Bourgogne Franche-Comté(FR)
Publications by Year
Research Areas
Liver physiology and pathology, Cancer, Hypoxia, and Metabolism, Cancer Mechanisms and Therapy, Renal cell carcinoma treatment, Cancer, Lipids, and Metabolism
Most-Cited Works
- → The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity(2019)2,187 cited
- → Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors(2019)690 cited
- Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality.(1998)
- → Fully Human Monoclonal Antibodies to Hepatocyte Growth Factor with Therapeutic Potential against Hepatocyte Growth Factor/c-Met–Dependent Human Tumors(2006)252 cited
- → Influences of neurotrophins on mammalian motoneurons in vivo(1993)198 cited
- → Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody(2010)148 cited
- → AMG 102, A Fully Human Anti-Hepatocyte Growth Factor/Scatter Factor Neutralizing Antibody, Enhances the Efficacy of Temozolomide or Docetaxel in U-87 MG Cells and Xenografts