Yoichi Iimura
Tokyo Medical University(JP)
Publications by Year
Research Areas
Cholinesterase and Neurodegenerative Diseases, Chemical synthesis and alkaloids, Asymmetric Synthesis and Catalysis, Computational Drug Discovery Methods, Synthesis and biological activity
Most-Cited Works
- → Novel piperidine derivatives. Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[2-(N-benzoylamino)ethyl]piperidine derivatives(1990)82 cited
- → Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-(2-phthalimidoethyl)piperidine, and related derivatives(1992)64 cited
- → Practical Synthesis of Chiral Emopamil Left Hand as a Bioactive Motif(2002)31 cited
- → Model experiments of otoconia stability after canalith repositioning procedure of BPPV(2010)11 cited
- → Is subnanomolar binding affinity required for the in vivo imaging of acetylcholinesterase? Studies on 18F-labeled G379(2006)7 cited
- → Discovery of novel neuronal voltage-Dependent calcium channel blockers based on emopamil left hand as a bioactive template(2003)5 cited
- → Enantioselective synthesis of (2S)-5-{4-[2-(4-fluorophenoxy)ethyl]piperazin-1-yl}-2-isopropyl-2-phenyl-pentanenitrile dihydrochloride (E2050) using enzyme-catalyzed kinetic resolution(2002)3 cited
- → The New Generation of Acetylcholinesterase Inhibitors(2002)2 cited