Paul S. Watson
Merck (Japan)(JP)Inspire Institute(US)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Synthesis and Biological Evaluation, Asymmetric Synthesis and Catalysis, Microbial Natural Products and Biosynthesis, Carbohydrate Chemistry and Synthesis
Most-Cited Works
- → A Diastereoselective Synthesis of 2,4-Disubstituted Piperidines: Scaffolds for Drug Discovery(2000)312 cited
- → Nonconventional Stereochemical Issues in the Design of the Synthesis of the Vancomycin Antibiotics: Challenges Imposed by Axial and Nonplanar Chiral Elements in the Heptapeptide Aglycons(1998)160 cited
- → Indazoles: Regioselective Protection and Subsequent Amine Coupling Reactions(2009)82 cited
- → Approaches to the Synthesis of the Vancomycin Antibiotics. Synthesis of Orienticin C (Bis-dechlorovancomycin) Aglycon(1997)79 cited
- → Unkonventionelle stereochemische Fragestellungen bei der Planung der Synthese von Vancomycin-Antibiotika: Herausforderungen durch axial- und nicht-planar-chirale Elemente der Heptapeptid-Aglyconbausteine(1998)58 cited
- → Addition of zinc homoenolates to acetylenic esters and amides: a formal [3 + 2] cycloaddition(1993)50 cited
- → Synthesis of the orienticin C M(2–4) macrocycle utilizing a nucleophilic aromatic substitution strategy(1996)47 cited
- → CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure–activity relationships(2002)46 cited
- → Lipophilic Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y12 Receptor(2008)38 cited
- → From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: The discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis(2007)30 cited