Ian Tomlinson
University Hospitals Birmingham NHS Foundation Trust(GB)University of Oxford(GB)
Publications by Year
Research Areas
Genetic factors in colorectal cancer, Cancer Genomics and Diagnostics, DNA Repair Mechanisms, Pancreatic and Hepatic Oncology Research, Carcinogens and Genotoxicity Assessment
Most-Cited Works
- → The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis(1999)370 cited
- → The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase(2003)153 cited
- → Inherited susceptibility to colorectal adenomas and carcinomas: Evidence for a new predisposition gene on 15q14-q22(1999)111 cited
- → Different Pathways of Colorectal Carcinogenesis and Their Clinical Pictures(2000)6 cited
- → Germline haploinsufficiency for the base excision repair gene MUTYH causes mutational signature SBS18 in multiple tumour types, specifically leading to an increased risk of colorectal cancer(2025)