Satoru Asahi
Takeda (Japan)(JP)
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Pharmacogenetics and Drug Metabolism, Pharmacological Effects and Toxicity Studies, Biochemical and Molecular Research, Enzyme Structure and Function
Most-Cited Works
- → Roles of NADPH-P450 Reductase and Apo- and Holo-Cytochrome b5 on Xenobiotic Oxidations Catalyzed by 12 Recombinant Human Cytochrome P450s Expressed in Membranes of Escherichia coli(2002)232 cited
- → Novel Inhibitor of p38 MAP Kinase as an Anti-TNF-α Drug: Discovery of N-[4-[2-Ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridyl]benzamide (TAK-715) as a Potent and Orally Active Anti-Rheumatoid Arthritis Agent(2005)145 cited
- → Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer(2011)126 cited
- → Establishment and Characterization of the Transformants Stably-Expressing MDR1 Derived from Various Animal Species in LLC-PK1(2006)125 cited
- → Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: Effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys(2012)116 cited
- → Kinetic Analyses for Species Differences in P-glycoprotein-Mediated Drug Transport(2006)110 cited
- → Enhancement of Cytochrome P-450 3A4 Catalytic Activities by Cytochrome b5 in Bacterial Membranes(1999)69 cited
- → Formation of A Dihydroxy Metabolite of Phenytoin in Human Liver Microsomes/cytosol: Roles of Cytochromes P450 2c9, 2c19, and 3a4(2000)68 cited
- → In vitro metabolism of TAK-438, vonoprazan fumarate, a novel potassium-competitive acid blocker(2016)66 cited
- → A validated simultaneous quantification method for vonoprazan (TAK-438F) and its 4 metabolites in human plasma by the liquid chromatography-tandem mass spectrometry(2016)38 cited