Arthur D. Clark
Rutgers, The State University of New Jersey(US)Advanced Pharma(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, HIV Research and Treatment, Biochemical and Molecular Research, DNA and Nucleic Acid Chemistry, RNA and protein synthesis mechanisms
Most-Cited Works
- → Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.(1993)1,105 cited
- → Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants(2004)511 cited
- → Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA(2001)404 cited
- → High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: Strategic flexibility explains potency against resistance mutations(2008)335 cited
- → Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody fab fragment at 2.8 Å resolution(1998)322 cited
- → Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids(1999)303 cited
- → Inhibition of Bacterial RNA Polymerase by Streptolydigin: Stabilization of a Straight-Bridge-Helix Active-Center Conformation(2005)197 cited
- → The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance(2001)194 cited
- → Crystal Structures of 8-Cl and 9-Cl TIBO Complexed with Wild-type HIV-1 RT and 8-Cl TIBO Complexed with the Tyr181Cys HIV-1 RT Drug-resistant Mutant(1996)187 cited
- → Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations(1992)187 cited