Sanjeev Shangary
MIT World Peace University(IN)
Publications by Year
Research Areas
Cancer-related Molecular Pathways, Cell death mechanisms and regulation, Ubiquitin and proteasome pathways, RNA Interference and Gene Delivery, Glycosylation and Glycoproteins Research
Most-Cited Works
- → Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction(2006)684 cited
- → Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition(2008)652 cited
- → Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy(2008)614 cited
- → Targeting the MDM2-p53 Interaction for Cancer Therapy(2008)368 cited
- → SAR405838: An Optimized Inhibitor of MDM2–p53 Interaction That Induces Complete and Durable Tumor Regression(2014)336 cited
- → Structure-Based Design of Potent Small-Molecule Inhibitors of Anti-Apoptotic Bcl-2 Proteins(2006)294 cited
- → SM-164: A Novel, Bivalent Smac Mimetic That Induces Apoptosis and Tumor Regression by Concurrent Removal of the Blockade of cIAP-1/2 and XIAP(2008)200 cited
- → Potent and Orally Active Small-Molecule Inhibitors of the MDM2−p53 Interaction(2009)176 cited
- → Discovery of a Nanomolar Inhibitor of the Human Murine Double Minute 2 (MDM2)−p53 Interaction through an Integrated, Virtual Database Screening Strategy(2006)114 cited
- → Peptides Derived from BH3 Domains of Bcl-2 Family Members: A Comparative Analysis of Inhibition of Bcl-2, Bcl-xL and Bax Oligomerization, Induction of Cytochrome c Release, and Activation of Cell Death(2002)98 cited