James V. Heck
Nexgenix Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Synthesis of β-Lactam Compounds, Peroxisome Proliferator-Activated Receptors, Antibiotic Resistance in Bacteria, Antibiotics Pharmacokinetics and Efficacy, Microbial Natural Products and Biosynthesis
Most-Cited Works
- → Structure−Function Studies on the New Growth Hormone-Releasing Peptide, Ghrelin: Minimal Sequence of Ghrelin Necessary for Activation of Growth Hormone Secretagogue Receptor 1a(2000)550 cited
- → Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice(1999)454 cited
- → Novel 2,3-Dihydrobenzofuran-2-carboxylic Acids: Highly Potent and Subtype-Selective PPARα Agonists with Potent Hypolipidemic Activity(2005)99 cited
- → Discovery of a Potent, Highly Selective, and Orally Efficacious Small-Molecule Activator of the Insulin Receptor(2000)87 cited
- → Design and Synthesis of α-Aryloxyphenylacetic Acid Derivatives: A Novel Class of PPARα/γ Dual Agonists with Potent Antihyperglycemic and Lipid Modulating Activity(2005)77 cited
- → Synthesis, stability, and biological evaluation of water-soluble prodrugs of a new echinocandin lipopeptide. Discovery of a potential clinical agent for the treatment of systemic candidiasis and Pneumocystis carinii pneumonia (PCP)(1992)71 cited
- → Activation of Insulin Signal Transduction Pathway and Anti-diabetic Activity of Small Molecule Insulin Receptor Activators(2000)67 cited
- → 5-Aryl thiazolidine-2,4-diones: discovery of PPAR dual α/γ agonists as antidiabetic agents(2003)57 cited
- → Preparation and structure-activity relationships of simplified analogs of the antifungal agent cilofungin: a total synthesis approach(1992)57 cited
- → (2R)-2-Ethylchromane-2-carboxylic Acids: Discovery of Novel PPARα/γ Dual Agonists as Antihyperglycemic and Hypolipidemic Agents(2004)56 cited