Steve Tam
Pfizer (United States)(US)
Publications by Year
Research Areas
Protease and Inhibitor Mechanisms, Peptidase Inhibition and Analysis, Cell Adhesion Molecules Research, Chemical Synthesis and Analysis, Cytokine Signaling Pathways and Interactions
Most-Cited Works
- → Synthesis and Biological Evaluation of Quinoline Salicylic Acids As P-Selectin Antagonists(2006)121 cited
- → Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis(2005)107 cited
- → A Selective Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Chronic Obstructive Pulmonary Disease (COPD): Discovery of (S)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408)(2009)103 cited
- → Synthesis and biological evaluation of sulfonamidooxazoles and β-keto sulfones: selective inhibitors of 11β-hydroxysteroid dehydrogenase type I(2005)84 cited
- → 2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[H]quinoline-4-carboxylic Acid (PSI-697): Identification of a Clinical Candidate from the Quinoline Salicylic Acid Series of P-Selectin Antagonists(2006)82 cited
- → Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors(2005)78 cited
- → Pharmacologic Inhibition of Tpl2 Blocks Inflammatory Responses in Primary Human Monocytes, Synoviocytes, and Blood(2007)76 cited
- → Selective functional inhibition of JAK‐3 is sufficient for efficacy in collagen‐induced arthritis in mice(2010)74 cited
- → Solid phase synthesis of directly linked PNA-DNA-hybrids(1995)69 cited
- → Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults(2010)68 cited