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C. Richard Hutchinson | doi.page

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C. Richard Hutchinson

Publications by Year

Research Areas

Microbial Natural Products and Biosynthesis, Genomics and Phylogenetic Studies, Carbohydrate Chemistry and Synthesis, Synthetic Organic Chemistry Methods, Plant Disease Resistance and Genetics

Most-Cited Works

→ Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis(1999)660 cited
→ Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699(1998)348 cited
→ A Model of Structure and Catalysis for Ketoreductase Domains in Modular Polyketide Synthases(2002)309 cited
→ Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus)(1989)287 cited
→ Metagenomic Analysis Reveals Diverse Polyketide Synthase Gene Clusters in Microorganisms Associated with the Marine Sponge Discodermia dissoluta(2005)272 cited
→ Precursor-Directed Biosynthesis of Erythromycin Analogs by an Engineered Polyketide Synthase(1997)259 cited

→ Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of polyketide antibiotic biosynthesis.(1989)251 cited

→ POLYKETIDE SYNTHASE GENE MANIPULATION: A Structure-Function Approach in Engineering Novel Antibiotics(1995)243 cited

→ Lovastatin Nonaketide Synthase Catalyzes an Intramolecular Diels−Alder Reaction of a Substrate Analogue(2000)232 cited

→ A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin.(1991)214 cited