Bindhu V. Karanam
Merck & Co., Inc., Rahway, NJ, USA (United States)(US)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Peroxisome Proliferator-Activated Receptors, Lipid metabolism and biosynthesis, Neuroscience and Neuropharmacology Research, Pain Mechanisms and Treatments
Most-Cited Works
- → Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes(2011)146 cited
- → In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: Identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism(1992)108 cited
- → Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity(2001)53 cited
- → Benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain(2007)46 cited
- → Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain(2014)41 cited
- → Trace level quantification of deuterated 17β‐estradiol and estrone in ovariectomized mouse plasma and brain using liquid chromatography/tandem mass spectrometry following dansylation reaction(2004)37 cited
- → 2-Arylindoles as gonadotropin releasing hormone (GnRH) antagonists: optimization of the tryptamine side chain(2002)37 cited
- → Imidazopyridines: A novel class of hNav1.7 channel blockers(2008)37 cited
- → Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase(2013)36 cited
- → Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans(2009)35 cited