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Jacobus P. D. van Veldhoven | doi.page

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Jacobus P. D. van Veldhoven

Leiden University(NL)Cleveland Clinic(US)Takasaki University of Health and Welfare(JP)Leiden University Medical Center(NL)Oncode Institute(NL)Centre for Human Drug Research(NL)University of Louisville Hospital(US)Boehringer Ingelheim (United States)(US)

Publications by Year

Research Areas

Receptor Mechanisms and Signaling, Adenosine and Purinergic Signaling, Neuropeptides and Animal Physiology, Pharmacological Receptor Mechanisms and Effects, Cardiac electrophysiology and arrhythmias

Most-Cited Works

→ Predicting Binding Affinities for GPCR Ligands Using Free-Energy Perturbation(2016)145 cited
→ False Positives in a Reporter Gene Assay: Identification and Synthesis of Substituted N-Pyridin-2-ylbenzamides as Competitive Inhibitors of Firefly Luciferase(2008)65 cited
→ Dual-Point Competition Association Assay: A Fast and High-Throughput Kinetic Screening Method for Assessing Ligand-Receptor Binding Kinetics(2012)65 cited
→ A Series of 2,4-Disubstituted Quinolines as a New Class of Allosteric Enhancers of the Adenosine A₃Receptor(2009)63 cited
→ Binding Kinetics of ZM241385 Derivatives at the Human Adenosine A_2A Receptor(2014)50 cited
→ Development of Covalent Ligands for G Protein-Coupled Receptors: A Case for the Human Adenosine A₃ Receptor(2019)45 cited

→ A new generation of adenosine receptor antagonists: From di- to trisubstituted aminopyrimidines(2008)44 cited

→ Pyrrolone Derivatives as Intracellular Allosteric Modulators for Chemokine Receptors: Selective and Dual-Targeting Inhibitors of CC Chemokine Receptors 1 and 2(2018)42 cited

→ Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A_2A Receptor(2021)40 cited

→ Protection from Myocardial Ischemia/Reperfusion Injury by a Positive Allosteric Modulator of the A3 Adenosine Receptor(2011)34 cited