Frank Halley
Sanofi (France)(FR)Smiths Detection (France)(FR)Ages et Vie(FR)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Estrogen and related hormone effects, Computational Drug Discovery Methods, Melanoma and MAPK Pathways, Advanced Breast Cancer Therapies
Most-Cited Works
- → Functionalization of saturated hydrocarbons. 14. Further studies on the mechanism of Gif-type systems(1989)116 cited
- → The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy(2001)90 cited
- → Discovery and Optimization of Pyrimidone Indoline Amide PI3Kβ Inhibitors for the Treatment of Phosphatase and Tensin Homologue (PTEN)-Deficient Cancers(2014)84 cited
- → Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer(2019)81 cited
- → An Algorithm-Directed Two-Component Library Synthesized Via Solid-Phase Methodology Yielding Potent and Orally Bioavailable p38 MAP Kinase Inhibitors(2002)73 cited
- → The chemistry of pentavalent organobismuth reagents. Part 7. The possible role of radical mechanisms in the phenylation process for bismuth(V), and related lead(IV), lodine(III), and antimony(V) reagents