Simon N. Haydar
Drug Discovery Laboratory (Norway)(NO)
Publications by Year
Research Areas
Nicotinic Acetylcholine Receptors Study, Receptor Mechanisms and Signaling, Cholinesterase and Neurodegenerative Diseases, Synthesis and Characterization of Heterocyclic Compounds, Synthesis and biological activity
Most-Cited Works
- → Procognitive and Neuroprotective Activity of a Novel α7 Nicotinic Acetylcholine Receptor Agonist for Treatment of Neurodegenerative and Cognitive Disorders(2009)99 cited
- → Neuronal Nicotinic Acetylcholine Receptors - Targets for the Development of Drugs to Treat Cognitive Impairment Associated with Schizophrenia and Alzheimers Disease(2010)94 cited
- → SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist(2009)41 cited
- → Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonists Containing a Urea Moiety: Identification and Characterization of the Potent, Selective, and Orally Efficacious Agonist 1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) Urea (SEN34625/WYE-103914)(2010)30 cited
- → Discovery of a Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonist Series and Characterization of the Potent, Selective, and Orally Efficacious Agonist 5-(4-Acetyl[1,4]diazepan-1-yl)pentanoic Acid [5-(4-Methoxyphenyl)-1H-pyrazol-3-yl] Amide (SEN15924, WAY-361789)(2012)26 cited
- → 5-Cyclic Amine-3-arylsulfonylindazoles as Novel 5-HT6 Receptor Antagonists(2010)22 cited
- → Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor(2014)21 cited
- → Preclinical assessment of an adjunctive treatment approach for cognitive impairment associated with schizophrenia using the alpha7 nicotinic acetylcholine receptor agonist WYE-103914/SEN34625(2011)20 cited
- → Heterobiaryl purine derivatives as potent antiproliferative agents: Inhibitors of cyclin dependent kinases. Part II(2009)16 cited
- → N-[5-(5-Fluoropyridin-3-yl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutyramide (SEN78702, WYE-308775): A Medicinal Chemistry Effort toward an α7 Nicotinic Acetylcholine Receptor Agonist Preclinical Candidate(2012)14 cited