Andrew S. Cook
Publications by Year
Research Areas
Historical Geography and Cartography, Epigenetics and DNA Methylation, Cancer-related gene regulation, Geographic Information Systems Studies, Porphyrin and Phthalocyanine Chemistry
Most-Cited Works
- → Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation(2011)538 cited
- → Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas(2016)218 cited
- → Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit(2012)195 cited
- → Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds(2018)175 cited
- → EZH2 Inhibitor Efficacy in Non-Hodgkin’s Lymphoma Does Not Require Suppression of H3K27 Monomethylation(2014)148 cited
- → Asymmetric Baylis–Hillman reactions: catalysis using a chiral pyrrolizidine base(1998)128 cited
- → Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib(2014)117 cited
- → A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction(2014)115 cited
- → The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action(2018)109 cited
- → Luminescence of rhenium(I) complexes with highly sterically hindered .alpha.-diimine ligands(1993)77 cited