Mario Girard
Merck Canada Inc. (Canada)(CA)
Publications by Year
Research Areas
Oxidative Organic Chemistry Reactions, Phosphodiesterase function and regulation, Cholinesterase and Neurodegenerative Diseases, Asymmetric Synthesis and Catalysis, Mercury impact and mitigation studies
Most-Cited Works
- → Asymmetric dihydroxylation of olefins with a simple chiral ligand(1993)88 cited
- → Optimization of a Tertiary Alcohol Series of Phosphodiesterase-4 (PDE4) Inhibitors: Structure−Activity Relationship Related to PDE4 Inhibition and Human Ether-a-go-go Related Gene Potassium Channel Binding Affinity(2003)66 cited
- → Discovery of L-791,943: A potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor(2002)56 cited
- → Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment(2010)43 cited
- Mercury levels in the Cree population of James Bay, Quebec, from 1988 to 1993/94.(1998)
- → An exception to the normal Mitsunobu reaction with phenols; the formation of hydrazones from salicylaldehydes(2005)26 cited
- → Optimization and structure–activity relationship of a series of 1-phenyl-1,8-naphthyridin-4-one-3-carboxamides: Identification of MK-0873, a potent and effective PDE4 inhibitor(2008)20 cited
- Varying mercury exposure with varying food source in a James Bay Cree community.(1996)
- → Cyclization of 2‐ and 3‐indolylthiobenzoic, phenylacetic and nicotinic acids and esters to novel indole‐containing tetracyclic ring systems(1999)12 cited
- → Cyclization of 2‐ and 3‐indolythioalkanoic acids to novel indole‐containing tricyclic ring systems(1996)11 cited