M S Hershfield
Duke University(US)
Publications by Year
Research Areas
Biochemical and Molecular Research, Adenosine and Purinergic Signaling, Cytomegalovirus and herpesvirus research, Immunodeficiency and Autoimmune Disorders, Virus-based gene therapy research
Most-Cited Works
- → Apparent suicide inactivation of human lymphoblast S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine and adenine arabinoside. A basis for direct toxic effects of analogs of adenosine.(1979)277 cited
- → Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma.(1989)227 cited
- → Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation.(1986)195 cited
- → In vivo inactivation of erythrocyte S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine in adenosine deaminase-deficient patients.(1979)168 cited
- Adenosine deaminase deficiency: clinical expression, molecular basis, and therapy.(1998)
- → Effects of mutational loss of adenosine kinase and deoxycytidine kinase on deoxyATP accumulation and deoxyadenosine toxicity in cultured CEM human T-lymphoblastoid cells.(1982)123 cited
- → IgG antibody response to polyethylene glycol-modified adenosine deaminase in patients with adenosine deaminase deficiency.(1992)113 cited
- → Use of site-directed mutagenesis to enhance the epitope-shielding effect of covalent modification of proteins with polyethylene glycol.(1991)105 cited
- → Immunoglobulin and T-cell receptor gene rearrangement and expression in human lymphoid leukemia cells at different stages of maturation.(1986)98 cited
- → Regulation of de novo purine synthesis in human lymphoblasts. Similar rates of de novo synthesis during growth by normal cells and mutants deficient in hypoxanthine-guanine phosphoribosyltransferase activity.(1977)96 cited