Chi-Chung Chan
Queen Elizabeth Hospital(GB)United Therapeutics (United States)(US)Queen Elizabeth Hospital(CN)
Publications by Year
Research Areas
Inflammatory mediators and NSAID effects, Estrogen and related hormone effects, Asthma and respiratory diseases, Synthesis and biological activity, Respiratory and Cough-Related Research
Most-Cited Works
- → L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor(1989)328 cited
- → Cyclooxygenase-2 Inhibitors. Synthesis and Pharmacological Activities of 5-Methanesulfonamido-1-indanone Derivatives(1995)71 cited
- → Synthesis and biological evaluation of both enantiomers of L-761,000 as inhibitors of cyclooxygenase 1 and 2(1996)68 cited
- → Reduction of animal usage by serial bleeding of mice for pharmacokinetic studies: application of robotic sample preparation and fast liquid chromatography–mass spectrometry(2001)51 cited
- → SAR in the alkoxy lactone series: the discovery of DFP, a potent and orally active COX-2 inhibitor(1999)45 cited
- → 3,4-Diaryl-5-hydroxyfuranones: highly selective inhibitors of cyclooxygenase-2 with aqueous solubility(2003)31 cited