Jian-Sung Wu
National Health Research Institutes(TW)
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Synthesis and biological activity, Cancer-related Molecular Pathways, Click Chemistry and Applications, Photosynthetic Processes and Mechanisms
Most-Cited Works
- → Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors(2013)136 cited
- → Scaffold-Hopping Strategy: Synthesis and Biological Evaluation of 5,6-Fused Bicyclic Heteroaromatics To Identify Orally Bioavailable Anticancer Agents(2011)95 cited
- → 5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors(2010)76 cited
- → Structure-Based Drug Design of Novel Aurora Kinase A Inhibitors: Structural Basis for Potency and Specificity(2009)74 cited
- → Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent in Vivo Pharmacodynamic Activity and Antitumor Efficacy(2015)74 cited
- → Cancer Cells Acquire Mitotic Drug Resistance Properties Through Beta I-Tubulin Mutations and Alterations in the Expression of Beta-Tubulin Isotypes(2010)57 cited
- → Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules(2013)55 cited
- → Mutagenesis of Dengue Virus Protein NS2A Revealed a Novel Domain Responsible for Virus-Induced Cytopathic Effect and Interactions between NS2A and NS2B Transmembrane Segments(2017)43 cited
- → Furanylazaindoles: Potent Anticancer Agents in Vitro and in Vivo(2013)43 cited
- → Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold(2008)31 cited