Betty Chan
Exicure (United States)(US)
Publications by Year
Research Areas
RNA modifications and cancer, RNA Research and Splicing, RNA and protein synthesis mechanisms, Acute Myeloid Leukemia Research, Protein Degradation and Inhibitors
Most-Cited Works
- → H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers(2018)500 cited
- → Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point(2015)458 cited
- → Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding(2020)159 cited
- → Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex(2017)148 cited
- → Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activityin vitroandin vivo(2005)109 cited
- → The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action(2018)109 cited
- → Plastic biochannel hybridization devices: a new concept for microfluidic DNA arrays(2002)95 cited
- → The use of glasgow coma scale in poisoning(1993)84 cited
- → Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening(2021)70 cited
- → Mechanisms of unintended amino acid sequence changes in recombinant monoclonal antibodies expressed in Chinese Hamster Ovary (CHO) cells(2010)67 cited