Dean Hickman
TB Alliance(US)Novosibirsk Tuberculosis Research Institute(RU)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Tuberculosis Research and Epidemiology, Pharmacovigilance and Adverse Drug Reactions, Computational Drug Discovery Methods, Pneumonia and Respiratory Infections
Most-Cited Works
- → Engineered human blood–brain barrier microfluidic model for vascular permeability analyses(2022)228 cited
- Evaluation of the selectivity of In vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities.(1998)
- → Discovery ofN-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N‘-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-Aminoindazole-Based Orally Active Multitargeted Receptor Tyrosine Kinase Inhibitor(2007)184 cited
- → N-acetyltransferase polymorphism(1991)171 cited
- → Potent Inhibition of the Cytochrome P-450 3A-Mediated Human Liver Microsomal Metabolism of a Novel HIV Protease Inhibitor by Ritonavir: A Positive Drug-Drug Interaction(1999)166 cited
- → Expression of arylamine N -acetyltransferase in human intestine(1998)141 cited
- → From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)