Jörg Keldenich
Bayer (Germany)(DE)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Analytical Chemistry and Chromatography, Pharmacogenetics and Drug Metabolism, Cancer, Hypoxia, and Metabolism, Erythropoietin and Anemia Treatment
Most-Cited Works
- → New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease(2002)327 cited
- → A Physiological Model for the Estimation of the Fraction Dose Absorbed in Humans(2004)223 cited
- → Mimicking Hypoxia to Treat Anemia: HIF-Stabilizer BAY 85-3934 (Molidustat) Stimulates Erythropoietin Production without Hypertensive Effects(2014)170 cited
- → COSMOmic: A Mechanistic Approach to the Calculation of Membrane−Water Partition Coefficients and Internal Distributions within Membranes and Micelles(2008)138 cited
- → In Silico ADMET Traffic Lights as a Tool for the Prioritization of HTS Hits(2006)113 cited
- → A Physiologic Model for Simulating Gastrointestinal Flow and Drug Absorption in Rats(2003)100 cited
- → CypScore: Quantitative Prediction of Reactivity toward Cytochromes P450 Based on Semiempirical Molecular Orbital Theory(2009)91 cited
- → Multilamellar Liposomes and Solid-Supported Lipid Membranes (TRANSIL): Screening of Lipid-Water Partitioning Toward a High-Throughput Scale(2001)75 cited
- → Discovery of Molidustat (BAY 85‐3934): A Small‐Molecule Oral HIF‐Prolyl Hydroxylase (HIF‐PH) Inhibitor for the Treatment of Renal Anemia(2018)75 cited
- → Solid-Supported Biomolecules on Modified Silica Surfaces—A Tool for Fast Physicochemical Characterization and High-Throughput Screening(2001)62 cited