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Akira Otaka | doi.page

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Akira Otaka

Tokushima University(JP)

Publications by Year

Research Areas

Chemical Synthesis and Analysis, Click Chemistry and Applications, Fluorine in Organic Chemistry, Synthesis and Catalytic Reactions, Carbohydrate Chemistry and Synthesis

Most-Cited Works

→ Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats(1987)359 cited
→ HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus(2004)307 cited
→ A Low-Molecular-Weight Inhibitor against the Chemokine Receptor CXCR4: A Strong Anti-HIV Peptide T140(1998)305 cited
→ T140 analogs as CXCR4 antagonists identified as anti‐metastatic agents in the treatment of breast cancer(2003)281 cited
→ Identification of Cell Binding Sites in the Laminin α1 Chain Carboxyl-terminal Globular Domain by Systematic Screening of Synthetic Peptides(1995)255 cited
→ Molecular‐Size Reduction of a Potent CXCR4‐Chemokine Antagonist Using Orthogonal Combination of Conformation‐ and Sequence‐Based Libraries(2003)202 cited

→ Chemical Synthesis of Biologically Active Monoglycosylated GM2‐Activator Protein Analogue Using N‐Sulfanylethylanilide Peptide(2013)

168 cited

→ Remodeling of gp41-C34 Peptide Leads to Highly Effective Inhibitors of the Fusion of HIV-1 with Target Cells We thank Dr. Terrence R. Burke, Jr., NCI, NIH, Frederick, MD 21702-1201, for proofreading the manuscript and providing useful comments. This research was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan, the Japan Society for the Promotion of Science, and the Japan Health Science Foundation.(2002)162 cited

→ Preparation of fluoro- and hydroxy-4-(phosphonomethyl)-D,L-phenylalanine suitably protected for solid-phase synthesis of peptides containing hydrolytically stable analogs of O-phosphotyrosine(1993)162 cited

→ A highly stereoselective synthesis of (E)-alkene dipeptide isosteres via organocyanocopper-Lewis acid mediation reaction(1991)152 cited