Purakkattle Biju
Merck & Co., Inc., Rahway, NJ, USA (United States)(US)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Chemokine receptors and signaling, Asymmetric Synthesis and Catalysis, Synthesis and biological activity, Chemical Synthesis and Analysis
Most-Cited Works
- → Discovery of 2-Hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): A Potent, Orally Bioavailable CXCR2/CXCR1 Receptor Antagonist(2006)113 cited
- → C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists(2007)43 cited
- → 3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists(2007)23 cited
- → Steroidal C-21 mercapto derivatives as dissociated steroids: Discovery of an inhaled dissociated steroid(2011)19 cited
- → Synthesis and structure–activity relationships of heteroaryl substituted-3,4-diamino-3-cyclobut-3-ene-1,2-dione CXCR2/CXCR1 receptor antagonists(2008)17 cited
- → New Methodology for the Synthesis of α,α-difluoroketones(2008)15 cited
- → Fluoroalkyl α side chain containing 3,4-diamino-cyclobutenediones as potent and orally bioavailable CXCR2–CXCR1 dual antagonists(2009)14 cited
- → 3,4-Diamino-1,2,5-thiadiazole as potent and selective CXCR2 antagonists(2009)13 cited
- → Discovery of aminoquinazoline derivatives as human A2A adenosine receptor antagonists(2015)13 cited
- → Aromatics to polyquinanes: A general method for the construction of tricyclo[6.3.0.04,8]-and tricyclo[6.3.0.02,6]undecanes(1999)11 cited