Kenneth D. Paull
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, Synthesis and biological activity, Computational Drug Discovery Methods, Synthesis and Biological Evaluation, Bioactive Compounds and Antitumor Agents
Most-Cited Works
- → Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell Lines(1991)3,244 cited
- Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.(1988)
- → Some practical considerations and applications of the national cancer institute in vitro anticancer drug discovery screen(1995)1,545 cited
- → An Information-Intensive Approach to the Molecular Pharmacology of Cancer(1997)1,178 cited
- → Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm(1989)969 cited
- → Comparison of In Vitro Anticancer-Drug-Screening Data Generated With a Tetrazolium Assay Versus a Protein Assay Against a Diverse Panel of Human Tumor Cell Lines(1990)928 cited
- → Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data(1991)376 cited
- → Neural Computing in Cancer Drug Development: Predicting Mechanism of Action(1992)310 cited
- → Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin(1993)195 cited
- Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data.(1992)