Jane R. Kenny
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Drug Transport and Resistance Mechanisms, Computational Drug Discovery Methods, Cytokine Signaling Pathways and Interactions, Drug-Induced Hepatotoxicity and Protection
Most-Cited Works
- → Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity(2011)136 cited
- → Special Section on Pharmacokinetic and Drug Metabolism Properties of Novel Therapeutic Modalities–Minireview(2019)118 cited
- → Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies(2012)110 cited
- → A Physiologically Based Pharmacokinetic Modeling Approach to Predict Disease–Drug Interactions: Suppression of CYP3A by IL-6(2013)107 cited
- → In Vitro–In Vivo Extrapolation of Clearance: Modeling Hepatic Metabolic Clearance of Highly Bound Drugs and Comparative Assessment with Existing Calculation Methods(2011)106 cited
- → Microphysiological systems for ADME-related applications: current status and recommendations for system development and characterization(2020)105 cited
- → Syntheses and Characterization of the Acyl Glucuronide and Hydroxy Metabolites of Diclofenac(2004)100 cited
- → EVALUATION OF TIME-DEPENDENT CYTOCHROME P450 INHIBITION USING CULTURED HUMAN HEPATOCYTES(2006)99 cited
- → Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model(2016)99 cited
- → AUTOMATED ASSESSMENT OF TIME-DEPENDENT INHIBITION OF HUMAN CYTOCHROME P450 ENZYMES USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY ANALYSIS(2005)96 cited