William E. Kohlbrenner
Abbott Fund(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, HIV Research and Treatment, Hepatitis C virus research, Click Chemistry and Applications, Influenza Virus Research Studies
Most-Cited Works
- → Design, Activity, and 2.8 Å Crystal Structure of a C 2 Symmetric Inhibitor Complexed to HIV-1 Protease(1990)528 cited
- → Structure-based, C2 symmetric inhibitors of HIV protease(1990)211 cited
- → Use of a Fluorescence Plate Reader for Measuring Kinetic Parameters with Inner Filter Effect Correction(1999)205 cited
- → Human Serum Attenuates the Activity of Protease Inhibitors toward Wild-Type and Mutant Human Immunodeficiency Virus(1998)177 cited
- → In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants with Increased Resistance to ABT-378, a Novel Protease Inhibitor(1998)171 cited
- → Antibacterial agents specifically inhibiting lipopolysaccharide synthesis(1987)142 cited
- → In Vitro Characterization of A-315675, a Highly Potent Inhibitor of A and B Strain Influenza Virus Neuraminidases and Influenza Virus Replication(2002)101 cited
- → New Quinolone Compounds from Pseudonocardia sp. with Selective and Potent Anti-Helicobacter pylori Activity: Taxonomy of Producing Strain, Fermentation, Isolation, Structural Elucidation and Biological Activities.(1998)68 cited
- → Structure-Based Characterization and Optimization of Novel Hydrophobic Binding Interactions in a Series of Pyrrolidine Influenza Neuraminidase Inhibitors(2005)59 cited
- → Design of orally bioavailable, symmetry-based inhibitors of HIV protease(1994)56 cited