Yung Chi Cheng
Yale University(US)
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, DNA and Nucleic Acid Chemistry, HIV/AIDS drug development and treatment, Lung Cancer Research Studies, Biochemical and Molecular Research
Most-Cited Works
- → Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)(1992)192 cited
- → Structure−Activity Relationships of 1-(2-Deoxy-2-fluoro-β-l-arabino- furanosyl)pyrimidine Nucleosides as Anti-Hepatitis B Virus Agents(1996)141 cited
- → Camptothecin induction of a time- and concentration-dependent decrease of topoisomerase I and its implication in camptothecin activity.(1995)99 cited
- RNA synthesis inhibitors alter the subnuclear distribution of DNA topoisomerase I.(1996)
- BIBW 22, a dipyridamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport.(1993)
- → Antitumor agents. 100. Inhibition of human DNA topoisomerase II by cytotoxic ether and ester derivatives of podophyllotoxin and .alpha.-peltatin(1989)39 cited
- → Antitumor agents. 78. Inhibition of human DNA topoisomerase II by podophyllotoxin and .alpha.-peltatin analogs(1986)36 cited
- → Synthesis and biological activities of 2-pyrimidinone nucleosides. 2. 5-Halo-2-pyrimidinone 2'-deoxyribosides(1985)32 cited
- → Degradation of Topoisomerase I Induced by Topoisomerase I Inhibitors Is Dependent on Inhibitor Structure but Independent of Cell Death(1999)24 cited
- → Dose escalation and pharmacokinetic study of irinotecan in combination with paclitaxel in patients with advanced cancer(2000)23 cited