Ian Kirby
London Biofoundry(GB)
Publications by Year
Research Areas
CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, Virus-based gene therapy research, T-cell and B-cell Immunology, Immune Cell Function and Interaction
Most-Cited Works
- → High resolution structures of HIV-1 RT from four RT–inhibitor complexes(1995)498 cited
- → Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery(2014)184 cited
- → Identification of Contact Residues and Definition of the CAR-Binding Site of Adenovirus Type 5 Fiber Protein(2000)182 cited
- → Mutations in the DG Loop of Adenovirus Type 5 Fiber Knob Protein Abolish High-Affinity Binding to Its Cellular Receptor CAR(1999)116 cited
- → Combined OX40L and mTOR blockade controls effector T cell activation while preserving T reg reconstitution after transplant(2017)80 cited
- → Molecular determinants of adenovirus serotype 5 fibre binding to its cellular receptor CAR.(1999)73 cited
- → 3′-Azido-3′-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes(1998)61 cited
- → Adenovirus Type 9 Fiber Knob Binds to the Coxsackie B Virus-Adenovirus Receptor (CAR) with Lower Affinity than Fiber Knobs of Other CAR-Binding Adenovirus Serotypes(2001)57 cited
- → The Human HLA-A*0201 Allele, Expressed in Hamster Cells, Is Not a High-Affinity Receptor for Adenovirus Type 5 Fiber(1999)55 cited
- → Adenovirus type 5 uptake by lung adenocarcinoma cells in culture correlates with Ad5 fibre binding is mediated by ?v?1 integrin and can be modulated by changes in ?1 integrin function(2001)53 cited