Grégoire Vuagniaux
Debiopharm (Switzerland)(CH)
Publications by Year
Research Areas
Cell death mechanisms and regulation, Hepatitis C virus research, RNA Interference and Gene Delivery, Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses
Most-Cited Works
- → Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy(2008)352 cited
- → Synergistic Activation of ENaC by Three Membrane-bound Channel-activating Serine Proteases (mCAP1, mCAP2, and mCAP3) and Serum- and Glucocorticoid-regulated Kinase (Sgk1) inXenopusOocytes(2002)223 cited
- → Activation of the Amiloride-Sensitive Epithelial Sodium Channel by the Serine Protease mCAP1 Expressed in a Mouse Cortical Collecting Duct Cell Line(2000)219 cited
- → The Isomerase Active Site of Cyclophilin A Is Critical for Hepatitis C Virus Replication(2009)194 cited
- → Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice(2007)184 cited
- → DEB025 (Alisporivir) Inhibits Hepatitis C Virus Replication by Preventing a Cyclophilin A Induced Cis-Trans Isomerisation in Domain II of NS5A(2010)181 cited
- → Debio 025, a Cyclophilin Binding Molecule, Is Highly Efficient in Clearing Hepatitis C Virus (HCV) Replicon-Containing Cells When Used Alone or in Combination with Specifically Targeted Antiviral Therapy for HCV (STAT-C) Inhibitors(2008)125 cited
- → HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A–cyclophilin A interaction to cyclophilin inhibitors(2010)120 cited
- → ENaC‐mediated alveolar fluid clearance and lung fluid balance depend on the channel‐activating protease 1(2009)99 cited
- → A Novel Neutrophil Elastase Inhibitor Prevents Elastase Activation and Surface Cleavage of the Epithelial Sodium Channel Expressed in Xenopus laevis Oocytes(2006)94 cited