Ginger Wu
Bristol-Myers Squibb (United States)(US)Discovery Laboratories (United States)(US)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Neurotransmitter Receptor Influence on Behavior, Chemical synthesis and alkaloids, Neuroscience and Neuropharmacology Research, Synthesis and pharmacology of benzodiazepine derivatives
Most-Cited Works
- → Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone(2001)484 cited
- → Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo(2015)51 cited
- → Discovery of 5-Chloro-4-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)oxy)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyridin-2(1H)-one (BMS-903452), an Antidiabetic Clinical Candidate Targeting GPR119(2014)45 cited
- → Discovery of ( R )-9-Ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1- a ]isoindol- 6(2 H )-one, a Selective, Orally Active Agonist of the 5-HT 2C Receptor(2007)33 cited
- → Tricyclic dihydroquinazolinones as novel 5-HT2C selective and orally efficacious anti-obesity agents(2009)20 cited
- → Utilization of an Active Site Mutant Receptor for the Identification of Potent and Selective Atypical 5-HT2CReceptor Agonists(2017)17 cited
- → Synthesis and SAR of potent and selective tetrahydropyrazinoisoquinolinone 5-HT2C receptor agonists(2013)15 cited
- → Synthesis and SAR of 2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-c]isoquinolin-5(9bH)-ones as 5-HT2C receptor agonists(2012)15 cited
- → Position 5.46 of the Serotonin 5-HT2A Receptor Contributes to a Species-Dependent Variation for the 5-HT2C Agonist (R)-9-Ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol-6(2H)-one: Impact on Selectivity and Toxicological Evaluation(2009)9 cited
- → CCDC 897809: Experimental Crystal Structure Determination(2013)