William J. Metzler
James Madison University(US)
Publications by Year
Research Areas
Protein Structure and Dynamics, Enzyme Structure and Function, DNA and Nucleic Acid Chemistry, RNA and protein synthesis mechanisms, Food Allergy and Anaphylaxis Research
Most-Cited Works
- → Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers(2011)136 cited
- → Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28(1997)133 cited
- → Involvement of DPP‐IV catalytic residues in enzyme–saxagliptin complex formation(2008)127 cited
- → Characterization of the three-dimensional solution structure of human profilin: proton, carbon-13, and nitrogen-15 NMR assignments and global folding pattern(1993)126 cited
- → Characterization of the Three-Dimensional Solution Structure of Human Profilin: 1H, 13C, and 15N NMR Assignments amd Global Folding Pattern(2001)119 cited
- → Use of 1HN-1HN NOEs to Determine Protein Global Folds in Perdeuterated Proteins(1995)117 cited
- → Identification of the poly-L-proline-binding site on human profilin.(1994)108 cited
- → Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13)(2005)93 cited
- → Incorporation of 1H/13C/15N-{Ile, Leu, Val} into a Perdeuterated, 15N-Labeled Protein: Potential in Structure Determination of Large Proteins by NMR(1996)84 cited
- → Limited sampling of conformational space by the distance geometry algorithm: implications for structures generated from NMR data(1989)74 cited