Tsutomu Higashijima
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Receptor Mechanisms and Signaling, Protein Kinase Regulation and GTPase Signaling, Healthcare and Venom Research, Neurobiology and Insect Physiology Research
Most-Cited Works
- → Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins).(1988)679 cited
- → Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity.(1990)602 cited
- → Effects of Mg2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteins.(1987)366 cited
- → Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1.(1992)344 cited
- → Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells.(1991)283 cited
- → The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins.(1986)261 cited
- → The effect of GTP and Mg2+ on the GTPase activity and the fluorescent properties of Go.(1987)232 cited
- → The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins.(1987)190 cited
- → Conformational change of mastoparan from wasp venom on binding with phospholipid membrane(1983)168 cited
- → Regulation of hormone-sensitive GTP-dependent regulatory proteins by chloride.(1987)138 cited