Karen Affleck
GlaxoSmithKline (United Kingdom)(GB)Age UK(GB)
Publications by Year
Research Areas
Asthma and respiratory diseases, HER2/EGFR in Cancer Research, Monoclonal and Polyclonal Antibodies Research, IL-33, ST2, and ILC Pathways, Mast cells and histamine
Most-Cited Works
- → A cellular census of human lungs identifies novel cell states in health and in asthma(2019)947 cited
- The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo.(2001)
- The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer.(2001)
- → hCLCA1 and mCLCA3 Are Secreted Non-integral Membrane Proteins and Therefore Are Not Ion Channels(2005)125 cited
- → EGFR blockade by tyrosine kinase inhibitor or monoclonal antibody inhibits growth, directs terminal differentiation and induces apoptosis in the human squamous cell carcinoma HN5.(1998)82 cited
- → Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and c-erbB-2(2001)80 cited
- → Discovery and Biological Evaluation of Potent Dual ErbB-2/EGFR Tyrosine Kinase Inhibitors: 6-Thiazolylquinazolines(2003)58 cited