a public good project by the
Synthesis
Company
of California

© 2026

Fritz Eckstein | doi.page

0 works0 citations0 h-index

Fritz Eckstein

Publications by Year

Research Areas

DNA and Nucleic Acid Chemistry, RNA and protein synthesis mechanisms, Advanced biosensing and bioanalysis techniques, RNA modifications and cancer, RNA Interference and Gene Delivery

Most-Cited Works

→ The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA(1985)849 cited
→ Nucleic Acids and Molecular Biology(1994)771 cited
→ Phosphorothioates, Essential Components of Therapeutic Oligonucleotides(2014)647 cited
→ Inhibition of restriction endonuclease Nel I cleavage by phosphorothioate groups and its application to oligonucleotide-directed mutagenesis(1986)553 cited
→ Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes(1991)468 cited
→ Phosphorothioate Oligodeoxynucleotides: What Is Their Origin and What Is Unique About Them?(2000)381 cited

→ Rapid and efficient synthesis of nucleoside 5'-0-(1-thiotriphosphates), 5'-triphosphates and 2',3'-cyclophosphorothioates using 2-chloro-4H-1,3,2-benzodioxaphosphorin-4-one(1989)

376 cited

→ 5′–3′ Exonucleases in phosphorothioate-based oligonucleotide-directed mutagenesis(1988)327 cited

→ MODIFIED OLIGONUCLEOTIDES: Synthesis and Strategy for Users(1998)310 cited

→ The Structure, Function and Application of the Hammerhead Ribozyme(1997)277 cited