Jan Balzarini
Rega Institute for Medical Research(BE)KU Leuven(BE)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, HIV Research and Treatment, Hepatitis C virus research, Cytomegalovirus and herpesvirus research, Biochemical and Molecular Research
Most-Cited Works
- → 9-(2-phosphonylmethoxyethyl)adenine (PMEA) effectively inhibits retrovirus replication in vitro and simian immunodeficiency virus infection in rhesus monkeys(1991)214 cited
- → A new class of HIV-1 specific 6-substituted acyclouridine derivatives: synthesis and anti-HIV-1 activity of 5- or 6-substituted analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)(1991)138 cited
- → Synthesis and evaluation of novel amidate prodrugs of PMEA and PMPA(2001)65 cited
- → Conversion of 2′,3′‐dideoxyadenosine (ddA) and 2′,3′‐didehydro‐2′,3′‐dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus(1997)60 cited
- → Cyclosaligenyl-2′,3′-didehydro-2′,3′-dideoxythymidine Monophosphate: Efficient Intracellular Delivery of d4TMP(2000)60 cited
- → Anti-HIV and Anti-HBV Activity and Resistance Profile of 2′,3′-Dideoxy-3′-Thiacytidine (3TC) and Its Arylphosphoramidate Derivative CF 1109(1996)60 cited
- → Synthesis of 3-Nitrosoimidazo[1,2-a]pyridine Derivatives as Potential Antiretroviral Agents(2001)20 cited
- → Mutations at Amino Acid Positions 63, 189, and 396 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase (RT) Partially Restore the DNA Polymerase Activity of a TRP229TYR Mutant RT(2001)17 cited
- → Lactate cannot substitute for alanine in D4T-based anti-HIV nucleotide prodrugs-despite efficient esterase-mediated hydrolysis(1998)8 cited