Julie K. Spence
AbbVie (United States)(US)
Publications by Year
Research Areas
Drug Solubulity and Delivery Systems, Advancements in Transdermal Drug Delivery, Crystallization and Solubility Studies, Phenothiazines and Benzothiazines Synthesis and Activities, Epigenetics and DNA Methylation
Most-Cited Works
- → A Win–Win Solution in Oral Delivery of Lipophilic Drugs: Supersaturation via Amorphous Solid Dispersions Increases Apparent Solubility without Sacrifice of Intestinal Membrane Permeability(2012)250 cited
- → The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia(2015)94 cited
- → A pH-Dilution Method for Estimation of Biorelevant Drug Solubility along the Gastrointestinal Tract: Application to Physiologically Based Pharmacokinetic Modeling(2010)73 cited
- → Comparison of artificial sebum with human and hamster sebum samples(2008)57 cited
- → Increased Dissolution Rate and Bioavailability Through Comicronization with Microcrystalline Cellulose(2005)21 cited
- → Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery(2010)12 cited
- → Synthesis of the Potassium Channel Opener (3S,4R)‐3,4‐Dihydro‐4‐(2,3‐dihydro‐2‐methyl‐3‐oxo‐pyridazin‐6‐Yl)oxy‐3‐hydroxy‐6‐(3‐hydroxyphenyl)sulphonyl‐2,2,3‐trimethyl‐2H‐benzo[b]pyran(2007)3 cited
- → ChemInform Abstract: Synthesis of the Potassium Channel Opener (3S,4R)‐3,4‐Dihydro‐4‐ (2,3‐dihydro‐2‐methyl‐3‐oxo‐pyridazin‐6‐yl)oxy‐3‐hydroxy‐6‐ (3‐hydroxyphenyl)sulfonyl‐2,2,3‐trimethyl‐2H‐benzo[b]pyran.(2008)