David J. Frost
Georgia Institute of Technology(US)
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, PARP inhibition in cancer therapy, Click Chemistry and Applications, Polysaccharides and Plant Cell Walls, Enzyme Production and Characterization
Most-Cited Works
- → ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models(2007)764 cited
- → Potent, Orally Active Heterocycle-Based Combretastatin A-4 Analogues: Synthesis, Structure−Activity Relationship, Pharmacokinetics, and In Vivo Antitumor Activity Evaluation(2002)420 cited
- → A Protein Farnesyltransferase Inhibitor Ameliorates Disease in a Mouse Model of Progeria(2006)311 cited
- → Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer(2008)266 cited
- → Activity of the Bcl-2 Family Inhibitor ABT-263 in a Panel of Small Cell Lung Cancer Xenograft Models(2008)209 cited
- → A Whole-Cell Candida albicans Assay for the Detection of Inhibitors towards Fungal Cell Wall Synthesis and Assembly.