Joseph J. McDonald
Publications by Year
Research Areas
Peptidase Inhibition and Analysis, Protease and Inhibitor Mechanisms, Signaling Pathways in Disease, Inflammatory mediators and NSAID effects, Protein Structure and Dynamics
Most-Cited Works
- → Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents(1996)1,868 cited
- → A Single Amino Acid Difference between Cyclooxygenase-1 (COX-1) and −2 (COX-2) Reverses the Selectivity of COX-2 Specific Inhibitors(1996)410 cited
- → Assessment of Docking Poses: Interactions-Based Accuracy Classification (IBAC) versus Crystal Structure Deviations(2004)125 cited
- → Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor(2002)101 cited
- → Crystal structure of the SALL4–pomalidomide–cereblon–DDB1 complex(2020)98 cited
- → Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease(2010)97 cited
- → Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease(2003)94 cited
- → Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality(2019)69 cited
- → Variations in the origin of arteries derived from the aortic arch, in American whites and negroes(1940)67 cited
- → Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy(2005)64 cited