Lora Swenson
Vertex Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Enzyme Catalysis and Immobilization, Enzyme Structure and Function, Microbial Metabolic Engineering and Bioproduction, Protein Kinase Regulation and GTPase Signaling, Enzyme Production and Characterization
Most-Cited Works
- → The Structural Basis for Autoinhibition of FLT3 by the Juxtamembrane Domain(2004)498 cited
- → Structure of GSK3beta reveals a primed phosphorylation mechanism.(2001)383 cited
- → The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity(2005)258 cited
- → Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships(2008)222 cited
- → The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity(2000)197 cited
- → Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar.(1994)196 cited
- → Crystal Structure of Aurora-2, an Oncogenic Serine/Threonine Kinase(2002)192 cited
- → Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism(2010)190 cited
- → Pim-1 Ligand-bound Structures Reveal the Mechanism of Serine/Threonine Kinase Inhibition by LY294002(2005)188 cited
- → Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer(1997)172 cited