Geoffrey Lawton
Roche (United Kingdom)(GB)
Publications by Year
Research Areas
Synthesis and Catalytic Reactions, Synthesis of β-Lactam Compounds, Protein Kinase Regulation and GTPase Signaling, Protease and Inhibitor Mechanisms, Cyclopropane Reaction Mechanisms
Most-Cited Works
- → Potent selective inhibitors of protein kinase C(1989)478 cited
- → Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity(1992)214 cited
- → Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides(1992)161 cited
- → Inhibitors of protein kinase C. 3. Potent and highly selective bisindolylmaleimides by conformational restriction(1993)156 cited
- → The design and synthesis of the Angiotensin Converting Enzyme inhibitor Cilazapril and related bicyclic compounds(1986)100 cited
- → The design and biological properties of potent and selective inhibitors of protein kinase C(1992)68 cited
- → K252a is a potent and selective inhibitor of phosphorylase kinase(1990)64 cited
- → A novel conformationally restricted protein kinase C inhibitor, Ro 31‐8425, inhibits human neutrophil superoxide generation by soluble, particulate and post‐receptor stimuli(1991)57 cited
- → New potent inhibitors of angiotensin converting enzyme(1984)53 cited
- Potent collagenase inhibitors prevent interleukin-1-induced cartilage degradation in vitro.(1991)