Erich L. Grimm
Merck Canada Inc. (Canada)(CA)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Asymmetric Synthesis and Catalysis, Chemical synthesis and alkaloids, Cell death mechanisms and regulation, Inflammatory mediators and NSAID effects
Most-Cited Works
- → Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte(2000)524 cited
- → Inhibition of Calpains Prevents Neuronal and Behavioral Deficits in an MPTP Mouse Model of Parkinson's Disease(2003)273 cited
- → Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886(2005)142 cited
- → Catalytic activity of caspase-3 is required for its degradation: stabilization of the active complex by synthetic inhibitors(2004)119 cited
- → Caspase-7 Expanded Function and Intrinsic Expression Level Underlies Strain-Specific Brain Phenotype ofCaspase-3-Null Mice(2004)100 cited
- → Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis(2004)86 cited
- → The Discovery of Setileuton, a Potent and Selective 5-Lipoxygenase Inhibitor(2010)79 cited
- → Caspase Inhibitors Attenuate 1-Methyl-4-Phenylpyridinium Toxicity in Primary Cultures of Mesencephalic Dopaminergic Neurons(2002)74 cited
- → Synthesis and biological evaluation of both enantiomers of L-761,000 as inhibitors of cyclooxygenase 1 and 2(1996)68 cited
- → Total synthesis of (±)-heliannuol A(1994)49 cited