Paule Lachance
Canadian Network for Innovation in Education(CA)
Publications by Year
Research Areas
Protease and Inhibitor Mechanisms, Peptidase Inhibition and Analysis, Signaling Pathways in Disease, Asymmetric Synthesis and Catalysis, Synthesis and characterization of novel inorganic/organometallic compounds
Most-Cited Works
- → The Papain-Like Protease from the Severe Acute Respiratory Syndrome Coronavirus Is a Deubiquitinating Enzyme(2005)384 cited
- → Selectivity in ISG15 and ubiquitin recognition by the SARS coronavirus papain-like protease(2007)166 cited
- → Functional expression of human cathepsin S in Saccharomyces cerevisiae. Purification and characterization of the recombinant enzyme.(1993)164 cited
- → Engineering the S2 subsite specificity of human cathepsin S to a cathepsin L- and cathepsin B-like specificity.(1994)90 cited
- → Design of Noncovalent Inhibitors of Human Cathepsin L. From the 96-Residue Proregion to Optimized Tripeptides(2002)75 cited
- → Carbon-13 nuclear magnetic resonance studies of organo alkali metal compounds. Models of polymerization systems(1975)62 cited
- → Small-Molecule Inhibitors of the Pseudaminic Acid Biosynthetic Pathway: Targeting Motility as a Key Bacterial Virulence Factor(2014)49 cited
- → Cathepsins X and B Can Be Differentiated through Their Respective Mono- and Dipeptidyl Carboxypeptidase Activities(2001)48 cited
- → Epoxysuccinyl dipeptides as selective inhibitors of cathepsin B(1993)45 cited
- → Contribution to Activity of Histidine−Aromatic, Amide−Aromatic, and Aromatic−Aromatic Interactions in the Extended Catalytic Site of Cysteine Proteinases(1996)38 cited