Charles W. Hutchins
AbbVie (United States)(US)
Publications by Year
Research Areas
Protein Tyrosine Phosphatases, Galectins and Cancer Biology, Receptor Mechanisms and Signaling, Computational Drug Discovery Methods, Protein Kinase Regulation and GTPase Signaling
Most-Cited Works
- → Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy(2003)226 cited
- → Fragment Screening and Assembly: A Highly Efficient Approach to a Selective and Cell Active Protein Tyrosine Phosphatase 1B Inhibitor(2003)161 cited
- → Aminopyridine-Based c-Jun N-Terminal Kinase Inhibitors with Cellular Activity and Minimal Cross-Kinase Activity(2006)159 cited
- → The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity(2023)151 cited
- → Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor(2017)134 cited
- → Discovery of ABT-267, a Pan-Genotypic Inhibitor of HCV NS5A(2014)126 cited